3-METHYL-5-PHENYL-4-ISOXAZOLECARBONYL CHLORIDE

3-METHYL-5-PHENYL-4-ISOXAZOLECARBONYL CHLORIDE - Names and Identifiers

Name	3-methyl-5-phenyl-4-isoxazolecarbonyl chloride
Synonyms	4-(Chlorocarbonyl)-3-methyl-5-phenylisoxazole 3-Methyl-5-phenylisoxazole-4-carbonyl chloride 3-METHYL-5-PHENYL-4-ISOXAZOLECARBONYL CHLORIDE 3-methyl-5-phenylisoxazole-4-carbonyl chloride 3-methyl-5-phenyl-4-isoxazolecarbonyl chloride
CAS	91182-77-3
InChI	InChI=1/C11H8ClNO2/c1-7-9(11(12)14)10(15-13-7)8-5-3-2-4-6-8/h2-6H,1H3

3-METHYL-5-PHENYL-4-ISOXAZOLECARBONYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C11H8ClNO2
Molar Mass	221.64
Density	1.278g/cm³
Boling Point	369.1°C at 760 mmHg
Flash Point	177°C
Vapor Presure	1.21E-05mmHg at 25°C
Storage Condition	Store under Nitrogen
Refractive Index	1.562

3-METHYL-5-PHENYL-4-ISOXAZOLECARBONYL CHLORIDE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

3-METHYL-5-PHENYL-4-ISOXAZOLECARBONYL CHLORIDE - Introduction

chloride is an organic compound whose chemical formula is C10H8ClNO2. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: chloride is white crystalline powder.
-Solubility: It is soluble in organic solvents, such as ether, chloroform and dimethyl sulfoxide.
-Melting point: about 90-95 ℃.
-Stability: It is relatively stable at room temperature.

Use:
chloride can be used as reaction intermediates in organic synthesis, specific applications include:
-Synthetic drugs: It can be used to synthesize biologically active drug molecules.
-Pesticide: It can be used to synthesize certain pesticides in the agricultural field.
-Sealant: It can be used as a sealant for metal surfaces.
-Ink material: It can be used for the preparation of dyes and inks.

Method:
The preparation method of chloride generally involves the following steps:
1. Benzoyl chloride reacts with dimethylnitrosamine under alkaline conditions to generate N-benzoyl-dimethylnitrosamine.
2. The obtained N-benzoyl-dimethylnitrosamine is reacted with potassium permanganate to generate N-benzoyl-N'-dimethyl-nitrogen pentoxide. Then, a hot acetic acid deoxidizer is added to react with trichloroammonia to form N-benzoyl-N'-dimethyl-isoxazole.
3. Finally, the generated N-benzoyl-N'-dimethyl-isoxazole is reacted with the chlorinated giant valve to generate the final product chloride.

Safety Information:
The following safety precautions should be paid attention to when handling chloride:
-This is an organic compound that may be toxic and irritating to the human body. Appropriate personal protective equipment should be worn when in contact.
-Avoid inhaling its dust or vapor, and should be used in a well-ventilated place.
-Avoid contact with skin, eyes and clothing. If there is contact, rinse immediately with plenty of water and seek medical help.
-Storage should be sealed, away from fire and flammable materials.
-Observe relevant regulations and safe operating procedures.

Last Update：2024-04-09 21:00:56